Interferential current (IFC) is a modality that uses electrical energy to manage pain as well as to stimulate tissue healing and muscle contraction. Instead of using low frequency current like electrical stimulation, IFC uses two currents at medium frequencies (1,000-10,000 Hz) reaching deeper tissues as they intersect. This method allows use of lower amplitude waves minimizing skin resistance and associated discomfort related to high amplitude waves at low frequencies. This project is a review of literature with respect to the efficacy of IFC in pain modulation. If efficacy is found, then appropriate parameters relative to the application of ICF will be discussed.